New study findings suggest that women who are trying to conceive should eat organic food, writes Myrto Ashe, M.D.
At-a-glance

  • A study published last year in the Journal of the American Medical Association suggests that pesticide residues in food may account for a large proportion of the roughly 100,000 unsuccessful pregnancy attempts in fertility clinics across North America.
  • The women in the study were grouped according to the amount of pesticides they ingested, as indicated by US Department of Agriculture data on average pesticide residue levels found in common foods.
  • The study found that the women in the highest quartile (the 25% of women who consumed the most pesticides) had a 26% reduced chance of having a live birth than women in the lowest quartile, who consumed the least amount of pesticides.
  • Women consuming the least pesticide had a 7% chance of miscarriage, while women consuming the most pesticide had a 34% chance of miscarriage.
  • The stunning implication of the study is that most infertile couples doing IVF would succeed in conceiving if they ate organic – or even “less poisonous”. This is proof that the food that we eat is not properly regulated.
  • Genetically modified (GM) herbicide-tolerant crops are grown with large amounts of herbicides, a class of pesticide. For this reason, GM foods should be avoided by women who want to conceive.

Pesticides are widely used chemicals that are impossible for most of us to avoid. Many people are aware that they impact weeds, insects, and fungi – as they are designed to do. But it is widely believed that they are harmless to humans at the low doses that they are exposed to through their diet.
However, a study published last year[1] in the Journal of the American Medical Association (JAMA) suggests that pesticide residues in food may account for a large proportion of the roughly 100,000 unsuccessful pregnancy attempts in fertility clinics across North America.
The women in the study were grouped according to the amount of pesticides they ingested, as indicated by US Department of Agriculture data on average pesticide residue levels found in common foods. The study found that the women in the highest quartile (the 25% of women who consumed the most pesticides) had a 26% reduced chance of having a live birth than women in the lowest quartile, who consumed the least amount of pesticides. These findings were statistically significant.
In terms of pregnancy loss (getting pregnant and miscarrying), women consuming the least pesticide had a 7% chance of miscarriage, while women consuming the most pesticide had a 34% chance of miscarriage. The authors believe that malfunctioning of the placenta is likely to be involved.
Study details
The JAMA study, conducted by researchers based at the Chan School of Public Health and other institutions in Boston, Massachusetts, followed women receiving fertility treatments at the Massachusetts General Hospital Fertility Center in Boston. At the time that the women enrolled in the fertility clinic, the researchers asked them to recall their dietary consumption of a number of foods – including commonly consumed fruits and vegetables such as apples, pears, spinach, and potatoes.
The typical content of pesticides for the patients’ foods was derived from annual reports from the US Department of Agriculture Pesticide Data Program.[2] Foods were classified as high or low-pesticide residue. The patients in the study underwent stimulation to produce eggs for in vitro fertilization. The researchers then focused on the outcomes that define a successful pregnancy: implantation of eggs, a positive ultrasound, and a live birth.
The study involved 325 women, some of whom had more than one cycle of assisted reproductive treatment. A total of 42% of the cycles resulted in a live birth. Total fruit and vegetable intake was not related to outcomes. However, the intake of fruits and vegetables that scored high for pesticide residues was correlated with a lower chance of having a live birth.
Implications
The authors of the JAMA study calculated that if women replaced just one serving per day of high pesticide residue produce with one serving per day of low pesticide residue produce, their chances of a live birth would improve by 88%.
A striking aspect of the study is that the subjects were not agricultural workers, suggesting that food intake does matter and occupational exposure is not the only concern.
Limitations
The study has some limitations. One is that it does not directly measure but only estimates pesticide consumption, based on the average levels of residues found in those foods recorded in the US Department of Agriculture (USDA) Pesticide Data Program database. However, the authors address this limitation by stating that in a previous study,[3] they were able to show that this method gives a good correlation with urinary levels of pesticides, thus providing a reliable measure of body pesticide burden. Future studies could add to our knowledge by measuring pesticide residues in the foods eaten and correlate these with urinary levels in the women.
Another limitation is that the study does not identify specific pesticides in the women’s diets, though the USDA database used does break down the pesticide residue measurements in different foods by individual pesticide types. This omission means that the study is not useful to scientists, farmers, and regulators who wish to prioritize restricting certain pesticides before others. However, the message to women who want to conceive is clear: they should minimize their exposure to all pesticides.
Other studies link adverse pregnancy outcomes to pesticides
Other studies have also found adverse impacts from pesticides on pregnancy and its outcomes:

  • The authors of the JAMA study quote 14 previous studies that confirm increased miscarriage rates and increased developmental abnormalities in children exposed to pesticides during their mother’s pregnancy.
  • Experiments in mice found that pesticides disrupt reproduction at low environmentally relevant doses that were claimed to be safe by US regulators. This effect was not seen at higher doses.[4] Such non-linear dose-response curves, as they are known, are common with substances that are endocrine (hormone) disruptors.[5]
  • A study on healthy pregnant women based in Norway showed adverse effects of eating foods grown with pesticides. Conversely, choosing organically grown vegetables during pregnancy was associated with a reduced risk of pre-eclampsia, a condition that affects some pregnant women and that involves high blood pressure and protein in the urine.[6] Consumption of organically produced foods during pregnancy was also associated with a lower prevalence of hypospadias, a birth defect in males in which the opening of the urethra is on the underside of the penis.[7]

Relevance to genetically modified (GM) crops
The relevance of the JAMA study to GM crops is that GM herbicide-tolerant crops are grown with large amounts of herbicides. However, the USDA database used in the study

  • does not include measurements of residues of glyphosate, the herbicide used on GM glyphosate-tolerant crops, which make up the large majority of GM crops grown worldwide, and
  • does not include measurements of residues in the raw commodity crops, of which a high proportion is GM herbicide-tolerant, such as soy and non-sweetcorn types of corn.

The USDA database does measure residues of two other herbicides that are increasingly being used with GM herbicide-tolerant crops, dicamba and 2,4-D. However, these herbicides are not used on crops for which a high proportion is made up of GM varieties.
The glyphosate problem
The best studied pesticide linked with GM crops is glyphosate. According to a peer-reviewed article published in 2016, global agricultural use of glyphosate increased following the adoption of glyphosate-tolerant GM crops in 1996.[8]
Another study found that GM glyphosate-tolerant soybeans contained high levels of residues of glyphosate and its toxic metabolite, AMPA (average of 3.3 and 5.7 mg/kg, respectively), while industrially grown non-GM soybeans and organic soybeans contained neither chemical.[9] Monsanto, the main developer of GM glyphosate-tolerant soybeans, previously called these levels “extreme”.[10] It now appears that “extreme” levels have become the norm.
GM soybeans grown in Argentina were found to have much higher levels of glyphosate, up to nearly 100 mg/kg. In seven out of eleven samples the level was higher than the international maximum residue level of 20 mg/kg allowed for soybean products used in human food and animal feed.[11]
Because of the widescale use of glyphosate on GM and other cropping systems, it is not surprising that surveys have found that the vast majority of people in the USA have readily detectable levels of glyphosate in their urine.[12] These findings should be of concern to women wishing to conceive because high glyphosate levels in urine have been correlated in a study to shortened pregnancy lengths.[13]
Conclusion
The stunning implication of the new study published in JAMA is that most infertile couples doing IVF would succeed in conceiving if they ate organic – or even “less poisonous”. This is proof that the food that we eat is not properly regulated.
References

  1. Yu-Han Chiu, MD, ScD; Paige L. Williams, PhD; Matthew W. Gillman, MD, SM; Audrey J. Gaskins, ScD; Lidia Mínguez-Alarcón, PhD; Irene Souter, MD; Thomas L. Toth, MD; Jennifer B. Ford, RN; Russ Hauser, MD, ScD; Jorge E. Chavarro, MD, ScD; EARTH Study Team. Association between pesticide residue intake from consumption of fruits and vegetables and pregnancy outcomes among women undergoing infertility treatment with assisted reproductive technology. JAMA Intern Med. 2018 Jan 1;178(1):17-26.
  2. US Department of Agriculture (USDA) Pesticide data program, annual summary, 2006-2012. Washington, DC: USDA, Agricultural Marketing Service; 2006-2012. https://www.ams.usda.gov/datasets/pdp/pdpdata.
  3. Hu Y, Chiu Y-H, Hauser R, Chavarro J, Sun Q. Overall and class-specific scores of pesticide residues from fruits and vegetables as a tool to rank intake of pesticide residues in United States: a validation study. Environ Int. 2016; 92-93: 294-300.
  4. Cavieres MF, Jaeger J, Porter W. Developmental toxicity of a commercial herbicide mixture in mice: 1. Effects on embryo implantation and litter size. Environ Health Perspect. 2002:110 (11):1081-5.
  5. Vandenberg LN et al. Hormones and endocrine-disrupting chemicals: Low-dose effects and nonmonotonic dose responses. Endocrine Reviews 2012;33(3):378–455.
  6. Torjusen H, Brantsæter AL, Haugen M, et al. Reduced risk of pre-eclampsia with organic vegetable consumption: results from the prospective Norwegian Mother and Child Cohort Study. BMJ Open. 2014;4(9):e006143.
  7. Brantsæter AL, Torjusen H, Meltzer HM, et al. Organic food consumption during pregnancy and hypospadias and cryptorchidism at birth: the Norwegian Mother and Child Cohort Study (MoBa). Environ Health Perspect. 2016;124(3):357-364.
  8. Benbrook CM. Trends in glyphosate herbicide use in the United States and globally. Environmental Sciences Europe 2016;28(3). https://link.springer.com/article/10.1186/s12302-016-0070-0
  9. Bøhn T, Cuhra M, Traavik T, Sanden M, Fagan J, Primicerio R. Compositional differences in soybeans on the market: glyphosate accumulates in Roundup Ready GM soybeans. Food Chem. 2013:153(2014):207–215.
  10. Bøhn T, Cuhra M. How “extreme” levels of Roundup in food became the industry norm. Independent Science News. March 2014. https://www.independentsciencenews.org/news/how-extreme-levels-of-roundup-in-food-became-the-industry-norm/
  11. Testbiotech. High levels of residues from spraying with glyphosate found in soybeans in Argentina. Munich, Germany; 2013. https://www.testbiotech.org/en/node/926
  12. Food Democracy Now! and The Detox Project (2017). Glyphosate: Unsafe on any plate. https://s3.amazonaws.com/media.fooddemocracynow.org/images/FDN_Glyphosate_FoodTesting_Report_p2016.pdf
  13. Parvez S, Gerona RR, Proctor C, et al. Glyphosate exposure in pregnancy and shortened gestational length: a prospective Indiana birth cohort study. Environmental Health 2018;17(23). https://doi.org/10.1186/s12940-018-0367-0

I just watched @justintegrity_ interview and films. In the large fog of delusion and deception cast by the C era, I'm moved by his willingness to stand up and tell the truth.

Dr. Patrick Whelan, the California doctor, said he filed a report with the Vaccine Adverse Event Reporting System (VAERS) after the boy suffered cardiac arrest shortly after taking a shot. The boy died about a week later.

Dr. Whelan tried updating the VAERS report to reflect the…

Parental Alert: "Loaded" cereals? That is correct, but with heavy metals and pesticides.

Hats off to @zenhoneycutt and @yesmaam74 for this scientific reporting that should have every parent clearing the cereal aisle.

@theNewMDS @stephanieseneff

Load More

V-Symposium Recordings:

GMOScience is offering these 2 days of recordings from April 2023 free of charge, featuring five of the top doctors, scientist, and attorney who are on the front lines, working with people experiencing adverse effects and injury from vaccine exposure and Long Covid. Please consider making a tax-deductible donation of any amount to support our work.

Contact Us

Contact

Related Posts

Hacked!

Hacked!

Artwork by Ruth Westreich; www.ruthwestreich.com Hacked! CEO, Dr. Michelle Perro discusses infant formula and heavy metal toxicity. On January 5,...

read more